GAK anticorps (C-Term)

N° du produit ABIN392633

Détail du produit anti-GAK anticorps

Antigène: GAK (Cyclin G Associated Kinase (GAK))

Épitope: AA 1140-1170, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1140-1170 amino acids from the C-terminal region of human GAK.

Clone: RB3949-3950

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur GAK

Antigène: GAK (Cyclin G Associated Kinase (GAK))

Autre désignation: GAK (GAK Produits)

Synonymes: anticorps GAK, anticorps DKFZp469F1313, anticorps gak, anticorps MGC172462, anticorps si:dkeyp-1e8.1, anticorps DNAJ26, anticorps DNAJC26, anticorps D130045N16Rik, anticorps cyclin G associated kinase, anticorps GAK, anticorps gak, anticorps Gak

Sujet: GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.

Poids moléculaire: 143191

ID gène: 2580

NCBI Accession: NP_005246

UniProt: O14976