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ULK2 anticorps (N-Term)

ULK2 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB12561 unconjugated
N° du produit ABIN392692
  • Antigène Voir toutes ULK2 Anticorps
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    Épitope
    • 12
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-264, N-Term
    Reactivité
    • 64
    • 17
    • 8
    Humain
    Hôte
    • 55
    • 9
    Lapin
    Clonalité
    • 56
    • 8
    Polyclonal
    Conjugué
    • 33
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ULK2 est non-conjugé
    Application
    • 48
    • 45
    • 15
    • 11
    • 10
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This ULK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the N-terminal region of human ULK2.
    Clone
    RB12561
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ULK2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    Autre désignation
    ULK2 (ULK2 Produits)
    Synonymes
    anticorps ULK2, anticorps ATG1B, anticorps Unc51.2, anticorps A830085I22Rik, anticorps AU015340, anticorps mKIAA0623, anticorps unc-51 like autophagy activating kinase 2, anticorps unc-51 like kinase 2, anticorps ULK2, anticorps Ulk2, anticorps ulk2
    Sujet
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Two human homologs of the yeast autophagy-specific kinase exist: ULK1(APG1) and ULK2. APG1 plays a critical role in regulating key elements of the autophagy pathway. APG1 stimulates autophagy, leading to autophagy-dependent restriction of cell growth and ultimately cell apoptosis at high levels of activity, and is a negative regulator of mTOR signaling.
    Poids moléculaire
    112694
    ID gène
    9706
    NCBI Accession
    NP_001136082, NP_055498
    UniProt
    Q8IYT8
    Pathways
    Regulation of Cell Size, Autophagy
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