Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This Natriuretic Peptide Receptor C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-97 amino acids from the N-terminal region of human Natriuretic Peptide Receptor C.
NPR3
Reactivité: Humain, Rat, Souris
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IF: 1:200. WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid freeze-thaw cycles.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
Date de péremption
6 months
Loo, Shepherd, Mickle, Lorca, Shutov, Usachev, Mohapatra: "The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical G??-dependent modulation of TRPV1 channel." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 35, pp. 11942-55, (2012) (PubMed).
Liu, Abendschein, Woodard, Rossin, McCommis, Zheng, Welch, Woodard: "Molecular imaging of atherosclerotic plaque with (64)Cu-labeled natriuretic peptide and PET." dans: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 51, Issue 1, pp. 85-91, (2010) (PubMed).
ANPC is a receptor for atrial natriuretic peptide. It does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.