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HK3 anticorps (C-Term)

HK3 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB3916 unconjugated
N° du produit ABIN392753
  • Antigène Voir toutes HK3 Anticorps
    HK3 (Hexokinase 3 (White Cell) (HK3))
    Épitope
    • 10
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 760-789, C-Term
    Reactivité
    • 51
    • 4
    • 2
    Humain, Souris
    Hôte
    • 48
    • 4
    Lapin
    Clonalité
    • 50
    • 2
    Polyclonal
    Conjugué
    • 26
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HK3 est non-conjugé
    Application
    • 33
    • 28
    • 22
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This HK3 (Hexokinase III) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 760-789 amino acids from the C-terminal region of human HK3 (Hexokinase III).
    Clone
    RB3916
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • van der Kooij, Rojas-Charry, Givehchi, Wolf, Bueno, Arndt, Tenzer, Mattioni, Treccani, Hasch, Schmeisser, Vianello, Giacomello, Methner: "Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels." dans: Journal of molecular medicine (Berlin, Germany), Vol. 100, Issue 10, pp. 1441-1453, (2022) (PubMed).

    Palmieri, Fitzgerald, Shreeve, Hua, Bronder, Weil, Davis, Stark, Merino, Kurek, Mehdorn, Davis, Steinberg, Meltzer, Aldape, Steeg: "Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis." dans: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1438-45, (2009) (PubMed).

  • Antigène
    HK3 (Hexokinase 3 (White Cell) (HK3))
    Autre désignation
    HK3 (Hexokinase III) (HK3 Produits)
    Synonymes
    anticorps HKIII, anticorps HXK3, anticorps APS, anticorps KLK2A1, anticorps PSA, anticorps hK3, anticorps HK III, anticorps HK-III, anticorps T2E6.5, anticorps T2E6_5, anticorps hexokinase 3, anticorps RNU73859, anticorps hexokinase 3, anticorps kallikrein related peptidase 3, anticorps HK3, anticorps KLK3, anticorps Hk3, anticorps HXK3
    Sujet
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).
    Poids moléculaire
    99025
    ID gène
    3101
    NCBI Accession
    NP_002106
    UniProt
    P52790
    Pathways
    Carbohydrate Homeostasis, L'effet Warburg
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