HK3 anticorps (N-Term)

N° du produit ABIN392754

Cité dans 1 publication. Cet anticorps anti-HK3 Polyclonal Lapin (Clone RB5335) (ABIN392754) détecte spécifiquement HK3 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HK3 anticorps (N-Term) (ABIN392754)

Antigène: HK3 (Hexokinase 3 (White Cell) (HK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HK3 est non-conjugé

Application: Western Blotting (WB)

Clone: RB5335

Détail du produit anti-HK3 anticorps

Épitope: AA 1-30, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This HK3 (Hexokinase III) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HK3 (Hexokinase III).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-HK3 (ABIN392754)

Palmieri, Fitzgerald, Shreeve, Hua, Bronder, Weil, Davis, Stark, Merino, Kurek, Mehdorn, Davis, Steinberg, Meltzer, Aldape, Steeg: "Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis." dans: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1438-45, (2009) (PubMed).

Détails sur HK3

Antigène: HK3 (Hexokinase 3 (White Cell) (HK3))

Autre désignation: HK3 (Hexokinase III)

Sujet: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.

Poids moléculaire: 99025

ID gène: 3101

NCBI Accession: NP_002106

UniProt: P52790

Pathways: Carbohydrate Homeostasis, L'effet Warburg