PIK3 gamma anticorps (AA 518-547)

N° du produit ABIN392817

Détail du produit anti-PIK3 gamma anticorps

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Épitope: AA 518-547

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3 gamma est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-547 amino acids from the Central region of human PI3KCG.

Clone: RB11630

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PIK3 gamma

Antigène: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Autre désignation: PI3KCG (PIK3CG Produits)

Synonymes: anticorps PI3CG, anticorps PI3K, anticorps PI3Kgamma, anticorps PIK3, anticorps Pi3k, anticorps wu:fb15d07, anticorps zgc:77033, anticorps pi3k, anticorps 5830428L06Rik, anticorps p110gamma, anticorps p120-PI3K, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma, anticorps si:rp71-17i16.5, anticorps PIK3CG, anticorps Pik3cg, anticorps pik3cg, anticorps si:rp71-17i16.5

Sujet: PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Poids moléculaire: 126454

ID gène: 5294

NCBI Accession: NP_001269355, NP_001269356, NP_002640

UniProt: P48736

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling