PTP4A3 anticorps
-
- Antigène Voir toutes PTP4A3 Anticorps
- PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PTP4A3 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogène
- This PRL3 antibody is generated from rabbits immunized with a recombinant protein encoding full length of human PRL3.
- Clone
- RB7265
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PTP4A3 Anticorps primaire
-
-
- Indications d'application
- WB: 1:1000. IHC-P: 1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
-
- Antigène
- PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
- Autre désignation
- PRL3 (PTP4A3 Produits)
- Synonymes
- anticorps PRL-3, anticorps PRL-R, anticorps PRL3, anticorps wu:fc54b05, anticorps wu:fv52d11, anticorps zgc:77109, anticorps prl-3, anticorps prl3, anticorps ptpcaax3, anticorps PTP4A3, anticorps AV088979, anticorps Prl-3, anticorps pPtp4a3, anticorps protein tyrosine phosphatase type IVA, member 3, anticorps protein tyrosine phosphatase type IVA, member 3 L homeolog, anticorps protein tyrosine phosphatase 4a3, anticorps PTP4A3, anticorps ptp4a3, anticorps ptp4a3.L, anticorps Ptp4a3
- Sujet
- The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. PRL-3 expression was found to be up-regulated in human liver carcinoma compared with normal liver. Its expression in colorectal cancers may contribute to the establishment of liver metastasis. In a different study, PRL-3 is found to be expressed in tumor metastasis and vasculature, regardless of the tumor source.
- Poids moléculaire
- 19535
- ID gène
- 11156
- NCBI Accession
- NP_009010, NP_116000
- UniProt
- O75365
-