DUSP4 anticorps (C-Term)

N° du produit ABIN392861

Détail du produit anti-DUSP4 anticorps

Antigène: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Épitope: AA 331-361, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This DUSP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human DUSP4.

Clone: RB05733

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur DUSP4

Antigène: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Autre désignation: DUSP4 (DUSP4 Produits)

Synonymes: anticorps zgc:55423, anticorps DUSP4, anticorps typ, anticorps hvh2, anticorps mkp2, anticorps mkp-2, anticorps MGC131045, anticorps HVH2, anticorps MKP-2, anticorps MKP2, anticorps TYP, anticorps 2700078F24Rik, anticorps AI844617, anticorps BB104621, anticorps E130306H24Rik, anticorps Mkp-2, anticorps Mkp2, anticorps dual specificity phosphatase 4, anticorps dual specificity phosphatase 4 S homeolog, anticorps dusp4, anticorps DUSP4, anticorps dusp4.S, anticorps Dusp4

Sujet: DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.

Poids moléculaire: 42953

ID gène: 1846

NCBI Accession: NP_001385, NP_476499

UniProt: Q13115

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades