DUSP14 anticorps (N-Term)

N° du produit ABIN392877

Détail du produit anti-DUSP14 anticorps

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Épitope: AA 1-30, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP14 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP14.

Clone: RB5911

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur DUSP14

Antigène: DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))

Autre désignation: DUSP14 (DUSP14 Produits)

Synonymes: anticorps MGC84083, anticorps zgc:101746, anticorps DUSP14, anticorps mkp-l, anticorps mkp6, anticorps MKP-L, anticorps MKP6, anticorps 1110014C10Rik, anticorps 2310042C07Rik, anticorps D11Ertd395e, anticorps Mkp6, anticorps dual specificity phosphatase 14, anticorps dual specificity phosphatase 14 L homeolog, anticorps DUSP14, anticorps dusp14.L, anticorps dusp14, anticorps Dusp14

Sujet: DUSP14 is involved in the inactivation of MAP kinases. This protein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 and B7-2 ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.

Poids moléculaire: 22255

ID gène: 11072

NCBI Accession: NP_008957

UniProt: O95147