USP18 anticorps (AA 40-49)

N° du produit ABIN401252

L’anticorps anti-USP18 Polyclonal Lapin est utilisé pour la détection de USP18 dans des échantillons de Humain, Chimpanzé et Orang-Utan. Il a été validé pour WB et EIA.

Aperçu rapide pour USP18 anticorps (AA 40-49) (ABIN401252)

Antigène: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Reactivité: Humain, Chimpanzé, Orang-Utan

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP18 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-USP18 anticorps

Épitope: AA 40-49

Specificité: This antibody is directed against human UBP43 protein.

Réactivité croisée (Details): Species reactivity (expected):A BLAST analysis was used to suggest reactivity with this protein from chimpanzee and orangutan based on 100 % homology for the immunogen sequence.
Species reactivity (tested):Human.

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide corresponding aa 40-49 of human UBP43 protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1: 10,000 - 1: 50,000. Western blot: 1: 500 - 1: 2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.9 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or for longer (in aliquots) at -20 °C or below.

Détails sur USP18

Antigène: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Autre désignation: USP18

Sujet: UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.Synonyms: 43 kDa ISG15-specific protease, ISG15-specific-processing protease, ISG43, Ubl carboxyl-terminal hydrolase 18, Ubl thioesterase 18

ID gène: 11274

NCBI Accession: NP_059110

UniProt: Q9UMW8