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PTENP1 anticorps (N-Term)

PTENP1 Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chimpanzé, Chien, Poisson-ballons vert, Macaque WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN401437
  • Antigène Tous les produits PTENP1
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chimpanzé, Chien, Poisson-ballons vert, Macaque
    Hôte
    • 2
    • 2
    Lapin
    Clonalité
    • 4
    Polyclonal
    Conjugué
    • 4
    Cet anticorp PTENP1 est non-conjugé
    Application
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Macaque, Chimpanzee, Opossum, Zebrafish, Green pufferfish, Platypus.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogène
    Purified peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein
    Isotype
    IgG
  • Indications d'application
    ELISA: 1/160,000. Western Blot: 1/500 to 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.73 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
  • Antigène
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Autre désignation
    PTENP1 (PTENP1 Produits)
    Synonymes
    anticorps PTEN-rs, anticorps PTEN2, anticorps PTENpg1, anticorps PTH2, anticorps psiPTEN, anticorps phosphatase and tensin homolog pseudogene 1, anticorps PTENP1
    Sujet
    This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.Synonyms: PTEN-rs, PTEN2, PTH2, Phosphatase and tensin homolog 2, Phosphatase and tensin homolog pseudogene 1, psiPTEN
    ID gène
    9606
    UniProt
    O43460
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