MYB anticorps (Internal Region)
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- Antigène Voir toutes MYB Anticorps
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat, Cheval, Porc, Singe, Opossum, Orang-Utan, Bonobo, Chimpanzé, Gorilla
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MYB est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts with endogenous c-Myb protein and also SUMOylated overexpressed c-Myb protein in transfected Cos7 cells.
- Purification
- Affinity chromatography
- Immunogène
- Peptide corresponding to an internal portion of the c-Myb protein
- Isotype
- IgG
- Top Product
- Discover our top product MYB Anticorps primaire
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- Indications d'application
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ELISA: 1/10,000 - 1/25,000. Western Blot: 1/250 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL (by UV absorbance at 280 nm)
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
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- Antigène
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
- Autre désignation
- MYB (MYB Produits)
- Synonymes
- anticorps Cmyb, anticorps c-myb, anticorps c-myb_CDS, anticorps efg, anticorps AI550390, anticorps M16449, anticorps cmyb, anticorps xmyb, anticorps MYB proto-oncogene, transcription factor, anticorps myeloblastosis oncogene, anticorps MYB proto-oncogene, transcription factor S homeolog, anticorps v-myb avian myeloblastosis viral oncogene homolog, anticorps MYB, anticorps Myb, anticorps myb.S, anticorps myb
- Sujet
- The transcription factor c-Myb plays an important role in the development of all hematopoietic lineages during definitive hematopoiesis. Its critical role in hematopoiesis has been first demonstrated in experiments with targeted disruption of the c-Myb gene where deletion of both alleles of the c-Myb gene was embryonally lethal due to severe anemia. c-Myb is a short-lived sequence specific DNA-binding protein that regulates transcription of several important genes involved directly in cellular processes such as proliferation, differentiation, and apoptosis. Posttranslational modifications such as phosphorylation, acetylation, ubiquitination, and conjugation of SUMO proteins are crucial for modulation of the transactivation activity of c-Myb.Synonyms: Proto-oncogene c-Myb, Transcriptional activator Myb, c-Myb
- ID gène
- 17863
- NCBI Accession
- NP_001185843
- UniProt
- P06876
- Pathways
- Chromatin Binding, Positive Regulation of Immune Effector Process
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