TREML1
Reactivité: Souris
IF (p), IF (cc)
Hôte: Lapin
Polyclonal
AbBy Fluor® 555
Indications d'application
Peptide ELISA: Antibody detection limit dilution 1: 2000. Western blot: 0.3-1 μg/mL. Approx 30 kDa band observed in Human Bone Marrow lysates(calculated MW of 32.0 kDa according to NP_835468.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Antigène
TREML1
(Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))
The TREMs (triggering receptors expressed on myeloid cells) represent a family of 5 receptors clustered on murine chromosome 17. TREM-like transcript-1 (TLT-1) was initially characterized as the putative inhibitory receptor within the TREM locus on chromosome 6 and was suggested to play a critical role in modulating TREM-associated immunity. It may also play a significant role in maintaining vascular hemostasis, coagulation, and inflammation at sites of injury through its location in platelets. TREML1 is the first ITIM-containing receptor carrying a potential Src homology 3 domain ligand. TREML1 transcripts are abundant in bone marrow cells, but not in lymphocytes, and phosphorylated TREML1 associates with SHP-1, suggesting that it is indeed an inhibitory receptor.Synonyms: TLT-1, TLT1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1