PCK1 anticorps (Internal Region)

N° du produit ABIN452441

Détail du produit anti-PCK1 anticorps

Antigène: PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PCK1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Recognizes PCK1/PEPCKC (internal).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human.

Purification: Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-HVNWFRKDKEGK, from the internal region of the protein sequence according to NP_002582.3.

Information d'application

Indications d'application: Peptide ELISA: Detection Limit: 1/8000. Immunohistochemistry: 2-4 μg/mL. In paraffin embedded Human Cerebral Cortex showsstaining of cytoplasm in pyramidal cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PCK1

Antigène: PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))

Autre désignation: PCK1 / PEPCK1 (PCK1 Produits)

Synonymes: anticorps PEPCK-C, anticorps PEPCK1, anticorps PEPCKC, anticorps PEPCK, anticorps PEPCK-M, anticorps PEPCK2, anticorps 1810010O14Rik, anticorps 9130022B02Rik, anticorps cb856, anticorps cb924, anticorps fj93h11, anticorps zgc:63869, anticorps wu:fc51c05, anticorps wu:fj93h11, anticorps pepck-c, anticorps pepck1, anticorps pepckc, anticorps PCK1, anticorps PPCK1, anticorps AI265463, anticorps Pck-1, anticorps GTP, anticorps PCK, anticorps Pepck, anticorps RATPEPCK, anticorps Ppc1C, anticorps PHOSPHOENOLPYRUVATE CARBOXYKINASE, anticorps T28I19.150, anticorps T28I19_150, anticorps phosphoenolpyruvate carboxykinase 1, anticorps 143299_at, anticorps CG10924, anticorps CG17725, anticorps Dmel\\CG17725, anticorps Dromel_CG17725_FBtr0086701_pepck_mORF, anticorps dPEPCK, anticorps pepck, anticorps PEPC, anticorps PEPCase, anticorps ppc, anticorps phosphoenolpyruvate carboxykinase 1, anticorps phosphoenolpyruvate carboxykinase 2, mitochondrial, anticorps phosphoenolpyruvate carboxykinase 2 (mitochondrial), anticorps phosphoenolpyruvate carboxykinase 1 (soluble), anticorps phosphoenolpyruvate carboxykinase 1 S homeolog, anticorps phosphoenolpyruvate carboxykinase, cytosolic [GTP], anticorps phosphoenolpyruvate carboxykinase 1, cytosolic, anticorps phosphoenolpyruvate carboxylase 7, anticorps Phosphoenolpyruvate carboxykinase, anticorps phosphoenolpyruvate carboxylase, anticorps PCK1, anticorps PCK2, anticorps Pck2, anticorps pck1, anticorps pck1.S, anticorps LOC100634531, anticorps Pck1, anticorps pep7, anticorps Pepck, anticorps LOC107777405

Sujet: PCK1 is a main control point for the regulation of gluconeogenesis. This cytosolic enzyme, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of the corresponding gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. A mitochondrial isozyme has also been characterized.Synonyms: PEP carboxykinase, PEPCK-C, PEPCKC, Phosphoenolpyruvate carboxykinase cytosolic [GTP], Phosphoenolpyruvate carboxylase

ID gène: 5105

NCBI Accession: NP_002582

UniProt: P35558

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis