SLC11A1
Reactivité: Humain
WB, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1/1,000. Western blotting: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène
SLC11A1
(Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))
anticorps SLC11A1, anticorps NRAMP1, anticorps LSH, anticorps NRAMP, anticorps Bcg, anticorps Itg, anticorps Lsh, anticorps Nramp1, anticorps Ity, anticorps Nramp, anticorps ity, anticorps BCG, anticorps solute carrier family 11 member 1 L homeolog, anticorps solute carrier family 11 member 1, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1, anticorps slc11a1.L, anticorps SLC11A1, anticorps Slc11a1
Sujet
NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.Synonyms: LSH, NRAMP, NRAMP-1, Natural resistance-associated macrophage protein 1, SLC11A1