Dynamin 3 anticorps (Middle Region)

N° du produit ABIN453622

Détail du produit anti-Dynamin 3 anticorps

Antigène: Dynamin 3 (DNM3)

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Dynamin-3 (DNM3).

Purification: Affinity Chromatography on Protein A.

Immunogène: KLH conjugated synthetic peptide selected from the Center region of Human Dynamin-3 (DNM3). Genename: DNM3

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Dynamin 3

Antigène: Dynamin 3 (DNM3)

Autre désignation: Dynamin-3 (DNM3 Produits)

Synonymes: anticorps DNM3, anticorps si:dkey-19f21.3, anticorps Dyna III, anticorps 9630020E24Rik, anticorps AW061159, anticorps B230343F03Rik, anticorps C530045C17, anticorps mKIAA0820, anticorps dynamin-2, anticorps dynamin 3, anticorps dynamin 3a, anticorps DNM3, anticorps dnm3a, anticorps Dnm3

Sujet: Dynamin 3 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin 3 is most probably involved in vesicular trafficking processes, in particular endocytosis. The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed, and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.Synonyms: DNM3, KIAA0820, T-dynamin

ID gène: 26052

NCBI Accession: NP_001129599

UniProt: Q9UQ16

Pathways: Toll-Like Receptors Cascades