kappa Light Chain anticorps

N° du produit ABIN457414

Détail du produit anti-kappa Light Chain anticorps

Antigène: kappa Light Chain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp kappa Light Chain est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.

Aucune reactivité croisée: Chévre, Cobaye, Hamster, Lapin, Mouton

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Clone: A8B5

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL, Positive control: Daudi human cell line.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-kappa Light Chain (ABIN457414)

Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." dans: Blood, Vol. 111, Issue 9, pp. 4706-15, (2008) (PubMed).

Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." dans: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, (1999) (PubMed).

Détails sur kappa Light Chain

Antigène: kappa Light Chain

Autre désignation: Kappa light chains (kappa Light Chain Produits)

Synonymes: anticorps LOC100037688, anticorps B128L, anticorps B55L, anticorps IgK, anticorps TCRAV31S1, anticorps TCRAV40S1, anticorps kappa light chain, anticorps immunoglobulin kappa chain variable 8 (V8), anticorps T cell receptor alpha variable 40, anticorps LOC100037688, anticorps Igk-V8, anticorps TRAV40

Sujet: Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin kappa, Igk