CD2 anticorps

N° du produit ABIN457428

Cité dans 1 publication. Cet anticorps anti-CD2 Monoclonal Souris (Clone LT2) (ABIN457428) détecte spécifiquement CD2 dans FACS et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD2 anticorps (ABIN457428)

Antigène: CD2

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD2 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: LT2

Détail du produit anti-CD2 anticorps

Fonction: Anti-Hu CD2 Purified

Specificité: The antibody LT2 reacts with an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 80 % (by SDS-PAGE)

Immunogène: Normal human blood lymphocytes.

Isotype: IgG2b

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-CD2 (ABIN457428)

Gannon, Rhind, Suzui, Zamecnik, Sabiston, Shek, Shephard: "beta-Endorphin and natural killer cell cytolytic activity during prolonged exercise. is there a connection?" dans: The American journal of physiology, Vol. 275, Issue 6 Pt 2, pp. R1725-34, (1999) (PubMed).

Détails sur CD2

Antigène: CD2

Autre désignation: CD2

Sujet: CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC

ID gène: 914

UniProt: P06729