CD81 anticorps
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- Antigène Voir toutes CD81 Anticorps
- CD81
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Reactivité
- Humain, Lapin, Cat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD81 est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Specificité
- The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
- Réactivité croisée (Details)
- Human, Feline (Cat), Rabbit
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- MOLT-4 (human T-ALL cell line)
- Clone
- M38
- Isotype
- IgG1
- Top Product
- Discover our top product CD81 Anticorps primaire
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- Indications d'application
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Flow cytometry: recommended dilution: 1 μg/mL.
Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6." dans: Cells, Vol. 9, Issue 6, (2020) (PubMed).
: "Subtypes of tumour cell-derived small extracellular vesicles having differently externalized phosphatidylserine." dans: Journal of extracellular vesicles, Vol. 8, Issue 1, pp. 1579541, (2019) (PubMed).
: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." dans: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).
: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).
: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).
: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." dans: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).
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New Role for Growth/Differentiation Factor 15 in the Survival of Transplanted Brown Adipose Tissues in Cooperation with Interleukin-6." dans: Cells, Vol. 9, Issue 6, (2020) (PubMed).
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- Antigène
- CD81
- Autre désignation
- CD81 (CD81 Produits)
- Sujet
- CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28
- ID gène
- 975
- UniProt
- P60033
- Pathways
- Inositol Metabolic Process, Hepatitis C
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