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ENPP3 anticorps

ENPP3 Reactivité: Humain FACS, ICC Hôte: Souris Monoclonal NP4D6 unconjugated
N° du produit ABIN457434
  • Antigène Voir toutes ENPP3 Anticorps
    ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
    Reactivité
    • 72
    • 34
    • 18
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 52
    • 20
    Souris
    Clonalité
    • 53
    • 19
    Monoclonal
    Conjugué
    • 22
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ENPP3 est non-conjugé
    Application
    • 33
    • 26
    • 26
    • 13
    • 13
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificité
    The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    HEK-293 cells transfected with human CD203c
    Clone
    NP4D6
    Isotype
    IgG1
    Top Product
    Discover our top product ENPP3 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL. Extracellular and intracellular staining.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Heneberg, Riegerová, Kučera: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).

    Platz, Binder, Marxer, Lischka, Valent, Bühring: "Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals." dans: International archives of allergy and immunology, Vol. 126, Issue 4, pp. 335-42, (2002) (PubMed).

  • Antigène
    ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
    Autre désignation
    CD203c (ENPP3 Produits)
    Synonymes
    anticorps B10, anticorps CD203c, anticorps NPP3, anticorps PD-IBETA, anticorps PDNP3, anticorps Npp3, anticorps RB13-6, anticorps AI876438, anticorps ENPP3, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 3, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 3 L homeolog, anticorps ENPP3, anticorps Enpp3, anticorps enpp3, anticorps enpp3.L
    Sujet
    Ectonucleotide pyrophosphatase/phosphodiesterase 3,CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.,ENPP3, B10, PDNP3, PD-IBETA
    ID gène
    5169
    UniProt
    O14638
    Pathways
    Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
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