PRR7 anticorps (C-Term, Intracellular)
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- Antigène Voir toutes PRR7 Anticorps
- PRR7 (Proline Rich 7 (Synaptic) (PRR7))
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Épitope
- C-Term, Intracellular
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Reactivité
- Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PRR7 est non-conjugé
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Application
- Western Blotting (WB), Immunocytochemistry (ICC)
- Specificité
- The mouse monoclonal antibody TRAP3/10 recognizes an epitope located in the C-terminal part of the intracellular domain of PRR7/TRAP3 (amino acids 126-253 of human PRR7 / TRAP3), a 28 kDa proline-rich membrane protein presumably associated with NMDA receptor complex.
- Réactivité croisée (Details)
- Human, Mouse, Rat
- Purification
- Purified by protein-A affinity chromatography.
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Recombinant C-terminal half of the intracellular domain of human PRR7/TRAP3 (amino acids 126-253)
- Clone
- TRAP3-10
- Isotype
- IgG2a
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- Indications d'application
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Immunocytochemistry: Recommended dilution: 10 μg/mL, cell culture fixed with 4 % paraformaldehyde, permeabilized with 0.1 % Triton-X100.
Western blotting: Recommended dilution: 1 μg/mL, positive control: murine brain lysate (red. Laemmli buffer). - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
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PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
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- Antigène
- PRR7 (Proline Rich 7 (Synaptic) (PRR7))
- Autre désignation
- PRR7 / TRAP3 (PRR7 Produits)
- Synonymes
- anticorps PRR7, anticorps XM_484263, anticorps proline rich 7, synaptic, anticorps proline rich 7 (synaptic), anticorps proline rich 7 (synaptic) L homeolog, anticorps PRR7, anticorps prr7, anticorps prr7.L, anticorps Prr7
- Sujet
- Proline rich 7, synaptic,PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.,TRAP3
- ID gène
- 80758
- UniProt
- Q8TB68
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