beta Amyloid anticorps
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- Antigène Voir toutes beta Amyloid (Abeta) Anticorps
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp beta Amyloid est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée (Details)
- Not reactive in: no confirmed exceptions from predicted reactivity known in the moment
- Homologie
- rat
- Attributs du produit
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Expected / apparent Molecular Weight of the Antigene: 4.5 kDa
OMAB antibody is a versatile tool within research of Alzheimer’s disease. A sandwhich ELISA illustrates its potential regarding its high selectivity towards Aβ oligomers. OMAB antibody has been purified by by ion-exchange chromatography. - Purification
- affinity purified
- Immunogène
- partly aggregated, recombinant peptide corresponding to the human Abeta (1-40/42). Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V. The epitope is 3-8.
- Clone
- OMAB
- Isotype
- IgM
- Top Product
- Discover our top product Abeta Anticorps primaire
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- Indications d'application
- coating antibody at 2 μg/mL (ELISA), 1: 500 (IHC)
- Commentaires
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OMAB antibody is a versatile tool within research of Alzheimer's disease. A sandwhich ELISA illustrates its potential regarding its high selectivity towards Aβ oligomers.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- For reconstitution add 100 μL of sterile water.
- Buffer
- PBS without any additives as carrier proteins or sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
- Stock
- 4 °C
- Stockage commentaire
- store lyophilized/reconstituted at 4°C. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
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- Antigène
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- Autre désignation
- Amyloid beta oligomer-specific (Abeta Produits)
- Sujet
- Soluble oligomeric assemblies of the Amyloid-β peptide are today anticipated to be the direct cause regarding the Alzheimer pathology. As a consequence, oligomeric Aβ-assemblies constitute a very interesting therapeutic target. Identification of Aβ-oligomers is however, technically challenging due to there labile nature and low abundance. Abeta oligomer-specific OMAB antibody is based on the IgM isotype and represents a new concept of Aβ-oligomer binders using a combination of high avidity and very low monovalent affinity. This combination creates a selectivity of the antibody towards the oligomeric fraction and minimizes reactivity towards monomeric species.
- Poids moléculaire
- 4.5 kDa
- Pathways
- Inflammasome
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