SPTLC1 anticorps

N° du produit ABIN4620353

Cet anticorps Lapin Polyclonal détecte spécifiquement SPTLC1 dans WB et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SPTLC1 anticorps (ABIN4620353)

Antigène: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPTLC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SPTLC1 anticorps

Specificité: This antibody detects Serine Palmitoyltransferase 1, ubiquitously expressed.

Purification: Antigen Immunoaffinity Chromatography

Immunogène: Synthetic peptide derived from the Human Sserine Palmitoyltransferase enzyme

Isotype: IgG

Information d'application

Indications d'application: Western Blot: (1-5 μg/mL). Immunohistochemistry: (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SPTLC1

Antigène: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Autre désignation: SPTLC1

Sujet: Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.Synonyms: LCB 1, LCB1, Long chain base biosynthesis protein 1, SPT 1, SPT1, Serine palmitoyltransferase 1, Serine-palmitoyl-CoA transferase 1

Poids moléculaire: 52.7 kDa

ID gène: 10558

NCBI Accession: NP_006406

UniProt: O15269