LNX1 anticorps
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- Antigène Voir toutes LNX1 Anticorps
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LNX1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects LNX1, expressed in heart, placenta, kidney, pancreas and brain.
- Purification
- Affinty chromatography
- Immunogène
- Synthetic peptide derived from the human LNX1 protein
- Top Product
- Discover our top product LNX1 Anticorps primaire
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- Indications d'application
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Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline with 0.08 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- Antigène
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
- Autre désignation
- LNX1 (LNX1 Produits)
- Synonymes
- anticorps LNX1, anticorps fj78f06, anticorps lnx, anticorps si:dkey-12h2.1, anticorps wu:fj78f06, anticorps zgc:152906, anticorps Lnx, anticorps LNX, anticorps MPDZ, anticorps PDZRN2, anticorps ligand of numb-protein X 1, anticorps LNX1, anticorps lnx1, anticorps Lnx1
- Sujet
- LNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.Synonyms: E3 ubiquitin-protein ligase LNX, LNX, LNX-1, Ligand of Numb-protein X 1, Numb-binding protein 1
- ID gène
- 84708
- NCBI Accession
- NP_001119800
- UniProt
- Q8TBB1
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