HLA-E anticorps

N° du produit ABIN462415

Détail du produit anti-HLA-E anticorps

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-E est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Recognized native surface-expressed HLA-E, but not denatured heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7

Purification: Protein A purified

Immunogène: Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.

Type of Immunogen: Synthetic peptide

Clone: MEM-E-06

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo, IHC, IHC-P (10 μg/mL), IP

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody,

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris buffered saline (TBS), 15 mM sodium azide, approx,  pH 8.0. Sourced in Ascites.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Détails sur HLA-E

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Autre désignation: HLA-E (HLA-E Produits)

Synonymes: anticorps EA1.2, anticorps EA2.1, anticorps HLA-6.2, anticorps MHC, anticorps QA1, anticorps major histocompatibility complex, class I, E, anticorps HLA-E, anticorps PATR-E

UniProt: P13747

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response