Desmoglein 1/2 anticorps (C-Term)
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- Antigène Tous les produits Desmoglein 1/2 (DSG1/2)
- Desmoglein 1/2 (DSG1/2)
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Épitope
- C-Term
- Reactivité
- Boeuf (Vache), Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Desmoglein 1/2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Species (tested so far) Human, bovine, rat, mouse. Recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells, does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165000 Desmoglein, 'band 3' polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ('RUD') of the cytoplasmic C-terminal part of the polypeptide. Reactivities on Cultured Cell Lines (tested so far): A-431, MCF-7, TR-146, PLC and various other human epithelial cell lines, bovine BMGE+H, BMGE-H, MDBK.
- Purification
- Protein A purified
- Immunogène
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Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis.
Type of Immunogen: Protein - Isotype
- IgG1
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- Indications d'application
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Approved: IF, IHC, IHC-Fr, IHC-P, WB
Usage: Suitable for use in Immunohistochemistry (frozen sections, paraffin-embedded tissue after microwave treatment), Western Blot, Cryo, Paraffin (Microwave), Immunofluorescence microscopy. Immunohistochemistry: 1:10 with PBS, pH 7.4, Incubation Time 1 h at RT, extended with paraffin. - Commentaires
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Target Species of Antibody: Bovine
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- deionized water
- Concentration
- Lot specific
- Buffer
- Lyophilized.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- Antigène
- Desmoglein 1/2 (DSG1/2)
- Autre désignation
- Desmoglein 1/2 (DSG1/DSG2) (DSG1/2 Produits)
- Synonymes
- anticorps DSG1, anticorps desmoglein 1, anticorps DSG1
- Sujet
- This antibody detects: DSG1+2 / Desmoglein 1+2
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