Insulin C-Peptide anticorps
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- Antigène Tous les produits Insulin C-Peptide
- Insulin C-Peptide
- Reactivité
- Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Insulin C-Peptide est non-conjugé
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Application
- ELISA
- Specificité
- Recognizes rat C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Recognizes rat and mouse C-peptide I and rat C-peptide II with equal affinity. Reacts weakly with mouse C-peptide II. It does not recognize rat proinsulin. May be used as a capture antibody in ELISA assays for rat or mouse C-peptides I or II.
- Purification
- Affinity purified
- Immunogène
- Fragments of rat C-peptide conjugated to a carrier protein.
- Clone
- CC34
- Isotype
- IgG1
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- Indications d'application
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Approved: ELISA, SwELISA
Usage: ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA ?to detect rat C-peptide I together with LS-C58408 as a detection reagent. These sandwich ELISA combinations are not suitable for the detection of mouse C-peptide I or II. - Commentaires
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Target Species of Antibody: Rat
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
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Short term: -20°C
Long term: -20°C.
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- Antigène
- Insulin C-Peptide
- Abstract
- Insulin C-Peptide Produits
- Synonymes
- anticorps IDDM2, anticorps ILPR, anticorps IRDN, anticorps MODY10, anticorps insulin, anticorps INS
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