ACLY anticorps (AA 1-180)

N° du produit ABIN4886416

Détail du produit anti-ACLY anticorps

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Épitope: AA 1-180

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACLY est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for ATP-citrate synthase(ACLY) detection. Tested with WB, IHC-P in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for ATP-citrate synthase(ACLY) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: ATP citrate lyase
Protein Name: ATP-citrate synthase

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human ATP citrate lyase recombinant protein (Position: M1-I180). Human ATP citrate lyase shares 95% amino acid (aa) sequence identity with both mouse and rat ATP citrate lyase.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ACLY

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Autre désignation: ACLY (ACLY Produits)

Synonymes: anticorps ACLY, anticorps DDBDRAFT_0205389, anticorps DDBDRAFT_0235360, anticorps DDB_0205389, anticorps DDB_0235360, anticorps ACL, anticorps BcDNA:LD21334, anticorps CG8322, anticorps DmATPCL, anticorps Dmel\\CG8322, anticorps anon-WO0140519.179, anticorps dATPCL, anticorps l(2)01466, anticorps l(2)k09217, anticorps n(2)k09217, anticorps ATPCL, anticorps CLATP, anticorps A730098H14Rik, anticorps AW538652, anticorps Clatp, anticorps acly, anticorps cb722, anticorps zgc:92008, anticorps ATP citrate lyase, anticorps ATP citrate lyase S homeolog, anticorps ATP-citrate synthase, anticorps citrate synthase, mitochondrial, anticorps atp-citrate synthase, anticorps ATP citrate lyase a, anticorps ACLY, anticorps acly.S, anticorps LOC587157, anticorps acly, anticorps ATPCL, anticorps LOC5564509, anticorps CpipJ_CPIJ010291, anticorps Bm1_26245, anticorps ACL, anticorps Acly, anticorps aclya

Sujet: ATP citrate lyase, aslo known as ACLY, is an enzyme that in animals represents an important step in fatty acid biosynthesis. ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer of apparently identical subunits. The product, acetyl-CoA, in animals serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. It is activated by insulin. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. In plants, ATP citrate lyase generates the acetyl-CoA for cytosolically-synthesized metabolites.

Synonyms: ACL | Acly | ATP citrate lyase | ATP citrate synthase | ATP-citrate synthase | ATPcitrate synthase | ATPCL | CLATP | P53396

ID gène: 47

UniProt: P53396

Pathways: L'effet Warburg