ADAR anticorps (AA 128-346)

N° du produit ABIN4886426

Détail du produit anti-ADAR anticorps

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Épitope: AA 128-346

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Double-stranded RNA-specific adenosine deaminase(ADAR) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Double-stranded RNA-specific adenosine deaminase(ADAR) detection. Tested with WB, IHC-P in Human.
Gene Name: adenosine deaminase, RNA-specific
Protein Name: Double-stranded RNA-specific adenosine deaminase

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ADAR1 recombinant protein (Position: S128-Q346). Human ADAR1 shares 90.2% and 50.7% amino acid (aa) sequence identity with mouse and rat ADAR1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ADAR

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Autre désignation: ADAR (ADAR Produits)

Synonymes: anticorps red1, anticorps drada, anticorps wu:fc22a02, anticorps adar1, anticorps dsRAD, anticorps dsRAD-1, anticorps ADAR, anticorps ADAR1, anticorps CG12598, anticorps Dmel\\CG12598, anticorps EG:BACN35H14.1, anticorps adar, anticorps adr, anticorps cg12598, anticorps dADAR, anticorps dAdar, anticorps hypnos-2, anticorps NV18763, anticorps AGS6, anticorps DRADA, anticorps DSH, anticorps DSRAD, anticorps G1P1, anticorps IFI-4, anticorps IFI4, anticorps K88DSRBP, anticorps P136, anticorps AV242451, anticorps Adar1, anticorps mZaADAR, anticorps adenosine deaminase, RNA-specific, anticorps adenosine deaminase, RNA-specific S homeolog, anticorps adenosine deaminase, RNA specific, anticorps Adenosine deaminase acting on RNA, anticorps adenosine deaminase acting on RNA, anticorps double-stranded RNA-specific editase 1, anticorps adar, anticorps adar.S, anticorps ADAR, anticorps Adar, anticorps CpipJ_CPIJ011849, anticorps LOC100114127

Sujet: Double-stranded RNA-specific adenosine deaminase, also known as ADAR1, is an enzyme that in humans is encoded by the ADAR gene. It is mapped to 1q21.3. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

Synonyms: Adar1 | Adar 1 | ADAR | AGS6 | AV242451 | DRADA | Dsh | Dsrad | G1P1 | IFI4 | IFI-4 | IFI 4 | P136 | P55265

ID gène: 103

UniProt: P55265

Pathways: Protein targeting to Nucleus