Adenylate Kinase 2 anticorps (AA 161-239)

N° du produit ABIN4886446

Détail du produit anti-Adenylate Kinase 2 anticorps

Antigène: Adenylate Kinase 2 (AK2)

Épitope: AA 161-239

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenylate Kinase 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Adenylate kinase 2, mitochondrial(AK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Adenylate kinase 2, mitochondrial(AK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: adenylate kinase 2
Protein Name: Adenylate kinase 2, mitochondrial

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human AK2 recombinant protein (Position: E161-I239). Human AK2 shares 93.7% and 93% amino acid (aa) sequence identity with mouse and rat AK2, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Adenylate Kinase 2

Antigène: Adenylate Kinase 2 (AK2)

Autre désignation: AK2 (AK2 Produits)

Synonymes: anticorps ADK-2, anticorps BcDNA:SD09634, anticorps CG3140, anticorps Dak2, anticorps Dmel\\CG3140, anticorps anon-Dak2, anticorps adk2, anticorps NV10896, anticorps wu:fb34f05, anticorps wu:fj80e03, anticorps ADK2, anticorps AK 2, anticorps Ak-2, anticorps D4Ertd220e, anticorps MXI22.8, anticorps MXI22_8, anticorps Adenylate kinase 2, anticorps adenylate kinase 2, anticorps adenylate kinase, anticorps adenylate kinase 2 S homeolog, anticorps Adenylate kinase family protein, anticorps Adk2, anticorps AK2, anticorps ak2, anticorps LOC100123971, anticorps ak2.S, anticorps Ak2, anticorps AT5G50370

Sujet: Adenylate kinase 2 is an enzyme is encoded in humans by the AK2 gene. The AK2 protein is found in the intermembrane space of the mitochondrion. Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates, this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.

Synonyms: Adenylate kinase 2 | ADK2 | AK 2 | ak2 | P54819

ID gène: 204

UniProt: P54819

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process