CPB2 anticorps (AA 166-388)

N° du produit ABIN4886545

Détail du produit anti-CPB2 anticorps

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Épitope: AA 166-388

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Carboxypeptidase B2(CPB2) detection. Tested with WB, IHC-P, ELISA in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Carboxypeptidase B2(CPB2) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: carboxypeptidase B2
Protein Name: Carboxypeptidase B2

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human CPB2 recombinant protein (Position: K166-D388). Human CPB2 shares 86.1% and 85.7% amino acid (aa) sequence identity with mouse and rat CPB2, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-CPB2 (ABIN4886545)

Qin, Zeng, Tian, Deng, Ren, Zheng, Li, Li, Liao, Chen: "Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats." dans: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 3, pp. 319-24, (2009) (PubMed).

Détails sur CPB2

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Autre désignation: CPB2 (CPB2 Produits)

Synonymes: anticorps CPU, anticorps PCPB, anticorps TAFI, anticorps 1110032P04Rik, anticorps 4930405E17Rik, anticorps AI255929, anticorps CPR, anticorps Cpu, anticorps pCPB, anticorps zgc:112493, anticorps carboxypeptidase B2, anticorps carboxypeptidase B2 (plasma), anticorps CPB2, anticorps Cpb2, anticorps cpb2

Sujet: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

Synonyms: Carboxypeptidase U | CarboxypeptidaseU | CarboxypeptidaseB2 | Carboxypeptidase B2 | CP B2 | CPB2 | CPB 2 | CPU | PCPB | Procarboxypeptidase B | Procarboxypeptidase R | Procarboxypeptidase U | TAFI | Q96IY4

ID gène: 1361

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis