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XPO1 anticorps (AA 966-1071)

XPO1 Reactivité: Humain, Souris, Rat WB, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4886771
  • Antigène Voir toutes XPO1 Anticorps
    XPO1 (Exportin 1 (XPO1))
    Épitope
    • 15
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 966-1071
    Reactivité
    • 72
    • 36
    • 35
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 66
    • 6
    Lapin
    Clonalité
    • 57
    • 15
    Polyclonal
    Conjugué
    • 39
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp XPO1 est non-conjugé
    Application
    • 45
    • 15
    • 15
    • 14
    • 14
    • 14
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Fonction
    Rabbit IgG polyclonal antibody for Exportin-1(XPO1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Exportin-1(XPO1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: exportin 1
    Protein Name: Exportin-1
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human CRM1 recombinant protein (Position: N966-D1071). Human CRM1 shares 93.4% and 91.5% amino acid (aa) sequence identity with mouse and rat CRM1, respectively.
    Isotype
    IgG
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    XPO1 (Exportin 1 (XPO1))
    Autre désignation
    XPO1 (XPO1 Produits)
    Synonymes
    anticorps CG13387, anticorps CRM1, anticorps Crm1, anticorps DCRM1, anticorps Dmel\\CG13387, anticorps Emb, anticorps XPO-1, anticorps XPO1, anticorps Xpo1, anticorps crm1, anticorps dCRM1, anticorps l(2)k16715, anticorps 18.m06600, anticorps DDBDRAFT_0183812, anticorps DDBDRAFT_0234066, anticorps DDB_0183812, anticorps DDB_0234066, anticorps exportin-1, anticorps LOC100220104, anticorps emb, anticorps exp1, anticorps Xpo, anticorps AA420417, anticorps Exp1, anticorps embargoed, anticorps exportin 1, anticorps putative exportin 1, anticorps chromosome region maintenance protein 1, anticorps exportin-1, anticorps exportin 1 (CRM1 homolog, yeast), anticorps exportin 1 S homeolog, anticorps emb, anticorps cgd3_3060, anticorps Tc00.1047053511725.150, anticorps Tb11.01.5940, anticorps BBOV_II007220, anticorps LMJF_32_1100, anticorps xpo1, anticorps Xpo1, anticorps XPO1, anticorps LOC100165622, anticorps LOC100633509, anticorps xpo1.S
    Sujet
    Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization. This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport. It specifically inhibits the nuclear export of Rev and U snRNAs. Additionally, this protein is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. It also regulates NFAT and AP-1.

    Synonyms: CRM 1 | CRM1 | emb | Exp 1 | Exp1 | Exportin1 | Exportin-1 | Exportin 1 | XPO1 | XPO 1 | O14980
    ID gène
    7514
    UniProt
    O14980
    Pathways
    M Phase
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