XPO1 anticorps (AA 966-1071)

N° du produit ABIN4886771

Détail du produit anti-XPO1 anticorps

Antigène: XPO1 (Exportin 1 (XPO1))

Épitope: AA 966-1071

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Fonction: Rabbit IgG polyclonal antibody for Exportin-1(XPO1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Exportin-1(XPO1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: exportin 1
Protein Name: Exportin-1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CRM1 recombinant protein (Position: N966-D1071). Human CRM1 shares 93.4% and 91.5% amino acid (aa) sequence identity with mouse and rat CRM1, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur XPO1

Antigène: XPO1 (Exportin 1 (XPO1))

Autre désignation: XPO1 (XPO1 Produits)

Synonymes: anticorps CG13387, anticorps CRM1, anticorps Crm1, anticorps DCRM1, anticorps Dmel\\CG13387, anticorps Emb, anticorps XPO-1, anticorps XPO1, anticorps Xpo1, anticorps crm1, anticorps dCRM1, anticorps l(2)k16715, anticorps 18.m06600, anticorps DDBDRAFT_0183812, anticorps DDBDRAFT_0234066, anticorps DDB_0183812, anticorps DDB_0234066, anticorps exportin-1, anticorps LOC100220104, anticorps emb, anticorps exp1, anticorps Xpo, anticorps AA420417, anticorps Exp1, anticorps embargoed, anticorps exportin 1, anticorps putative exportin 1, anticorps chromosome region maintenance protein 1, anticorps exportin-1, anticorps exportin 1 (CRM1 homolog, yeast), anticorps exportin 1 S homeolog, anticorps emb, anticorps cgd3_3060, anticorps Tc00.1047053511725.150, anticorps Tb11.01.5940, anticorps BBOV_II007220, anticorps LMJF_32_1100, anticorps xpo1, anticorps Xpo1, anticorps XPO1, anticorps LOC100165622, anticorps LOC100633509, anticorps xpo1.S

Sujet: Exportin 1 (XPO1), also known as chromosomal maintenance 1 (CRM1), is an eukaryotic protein that mapped to human chromosome 2p16 by fluorescence in situ hybridization. This protein mediates leucine-rich nuclear export signal (NES)-dependent protein transport. It specifically inhibits the nuclear export of Rev and U snRNAs. Additionally, this protein is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. It also regulates NFAT and AP-1.

Synonyms: CRM 1 | CRM1 | emb | Exp 1 | Exp1 | Exportin1 | Exportin-1 | Exportin 1 | XPO1 | XPO 1 | O14980

ID gène: 7514

UniProt: O14980

Pathways: M Phase