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FCAR anticorps

FCAR Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal A59 unconjugated
N° du produit ABIN4888509
  • Antigène Voir toutes FCAR Anticorps
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    Reactivité
    • 68
    • 21
    • 9
    • 4
    • 3
    Humain, Non-Human Primate
    Hôte
    • 49
    • 24
    Souris
    Clonalité
    • 50
    • 22
    • 1
    Monoclonal
    Conjugué
    • 30
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FCAR est non-conjugé
    Application
    • 28
    • 27
    • 19
    • 13
    • 13
    • 9
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody A59 recognizes an extracellular epitope of CD89, a 55-100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes and macrophages.
    Réactivité croisée (Details)
    Human, Non-Human Primates
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Ag8.653 myeloma cells
    Clone
    A59
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FCAR Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    Autre désignation
    CD89 (FCAR Produits)
    Synonymes
    anticorps CD89, anticorps Fc fragment of IgA receptor, anticorps Fc fragment of IgA, receptor for, anticorps FCAR
    Sujet
    Fc fragment of IgA receptor,CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes, monocytes, macrophages, dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes, stimulators (such as LPS, PMA), TNF alpha, IL1 beta or GM-CSF, and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense.,FcalphaRI, FcAR, CTB-61M7.2
    ID gène
    2204
    UniProt
    P24071
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