FOXO anticorps (N-Term)

N° du produit ABIN4889143

Détail du produit anti-FOXO anticorps

Antigène: FOXO (Forkhead Box, Sub-Group O (FOXO))

Épitope: N-Term

Reactivité: Drosophila melanogaster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: Reacts with the Drosophila melanogaster dFOXO protein

Purification: Purified (protein A)

Immunogène: Synthetic peptide derived from Nter domain of the Drosophila dFOXO protein.

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:2000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur FOXO

Antigène: FOXO (Forkhead Box, Sub-Group O (FOXO))

Autre désignation: Forkhead Box Protein O (dFOXO) (FOXO Produits)

Synonymes: anticorps 3143, anticorps Afx, anticorps CG3143, anticorps Dfoxo, anticorps DmQ95V5, anticorps Dmel\\CG3143, anticorps FKHR, anticorps FOXO, anticorps FoxO, anticorps Foxo, anticorps Q95V55, anticorps anon-WO0118547.374, anticorps cg3143, anticorps dFOXO, anticorps dFoxO, anticorps dFoxo, anticorps dfoxo, anticorps fd88A, anticorps foxO, anticorps foxo, anticorps forkhead box, sub-group O, anticorps foxo

Sujet: Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.

ID gène: 41709

UniProt: Q95V55

Pathways: Cellular Glucan Metabolic Process, Regulation of Cell Size