MYD88 anticorps (Internal Region)
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- Antigène Voir toutes MYD88 Anticorps
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat, Singe
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MYD88 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Reacts with Myd88 from human, mouse, rat, monkeys and other species (due to 100 % sequence homology)
- Purification
- Purified (protein A)
- Immunogène
- Synthetic peptide of derived from internal part of human Myd88
- Top Product
- Discover our top product MYD88 Anticorps primaire
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- Indications d'application
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Concentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Date de péremption
- 6 months
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- Antigène
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Autre désignation
- MyD88 (MYD88 Produits)
- Synonymes
- anticorps MYD88D, anticorps XMyD88, anticorps myd88d, anticorps MGC84928, anticorps CG2078, anticorps DMMYD88, anticorps DmMyD88, anticorps DmMyd88, anticorps Dmel\\CG2078, anticorps EP(2)2535, anticorps Kra, anticorps LD20892, anticorps MYD88, anticorps MyD88, anticorps Myd88F, anticorps dMyD88, anticorps dMyd88, anticorps kra, anticorps myd88, anticorps zgc:103541, anticorps GB12344, anticorps NV10640, anticorps myd88-a, anticorps myd88-b, anticorps myeloid differentiation primary response 88, anticorps myeloid differentiation primary response 88 S homeolog, anticorps myeloid differentiation primary response gene 88, anticorps CG2078 gene product from transcript CG2078-RB, anticorps myeloid differentiation primary response protein MyD88-A, anticorps myeloid differentiation primary response protein MyD88, anticorps myeloid differentiation factor 88, anticorps myeloid differentiation primary response 88 L homeolog, anticorps MYD88, anticorps myd88.S, anticorps Myd88, anticorps myd88, anticorps LOC413194, anticorps LOC100118553, anticorps LOC575153, anticorps myd88.L
- Sujet
- Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
- ID gène
- 4615
- UniProt
- Q99836
- Pathways
- Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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