RHOH anticorps (C-Term)
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- Antigène Voir toutes RHOH Anticorps
- RHOH (Ras Homolog Family Member H (RHOH))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RHOH est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- Reacts with human RhoH protein
- Purification
- Purified (protein A)
- Immunogène
- Synthetic peptide derived from C terminal domain of human RhoH
- Top Product
- Discover our top product RHOH Anticorps primaire
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- Indications d'application
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- IHC : 1/200 to 1/2 000 - WB : 1/500 to 1/5 000 - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Date de péremption
- 24 months
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- Antigène
- RHOH (Ras Homolog Family Member H (RHOH))
- Autre désignation
- rho-Related GTP-Binding Protein RhoH (RHOH Produits)
- Synonymes
- anticorps ARHH, anticorps TTF, anticorps 5830400A04Rik, anticorps AU019774, anticorps Arhh, anticorps ras homolog family member H, anticorps RHOH, anticorps Rhoh
- Sujet
- Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection.
- UniProt
- Q15669
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