NBR1 anticorps

N° du produit ABIN4901991

Détail du produit anti-NBR1 anticorps

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NBR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: NBR1 is a protein encoded by the NBR1 gene which is approximately 107,4 kDa. NBR1 is localised to the cytoplasm and is involved in animal mitophagy. It contains a B-box/coiled-coil motif and functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is expressed in the nervous system, bone marrow, lung and muscle. Mutations in the NBR1 gene may result in inclusion body myositis and synucleinopathy. STJ98902 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous NBR1 protein.

Specificité: The antibody detects endogenous NBR1 protein.

Attributs du produit: Mouse Monoclonal to NBR1.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Recombinant peptide derived from NBR1.

Information d'application

Indications d'application: WB 1:500-2000
ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur NBR1

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Autre désignation: NBR1 (NBR1 Produits)

Poids moléculaire: 120kDa

ID gène: 4077

UniProt: Q14596

Pathways: Autophagy