tau anticorps (AA 150-220)

N° du produit ABIN4902336

Détail du produit anti-tau anticorps

Antigène: tau (tau Protein)

Épitope: AA 150-220

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp tau est non-conjugé

Application: Western Blotting (WB), ELISA

Fonction: Tau is a protein encoded by the MAPT gene which is approximately 78,9 kDa. Tau is localised to the cytoplasm and cell membrane. It is involved in the apoptotic cleavage of cellular proteins, MAPK signalling pathway, CDK-mediated phosphorylation and removal of Cdc6 and development slit-robo signalling. It promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein. Tau is expressed in neurons. Mutations in the MAPT gene may result in Frontotemporal dementia. STJ98827 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Tau protein.

Specificité: The antibody detects endogenous Tau.

Attributs du produit: Rabbit Polyclonal to Tau.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthetic peptide from human Tau protein.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000
ELISA 1:5000-20000

Commentaires:

Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur tau

Antigène: tau (tau Protein)

Autre désignation: Tau (tau Produits)

Synonymes: anticorps DDPAC, anticorps FTDP-17, anticorps MAPTL, anticorps MSTD, anticorps MTBT1, anticorps MTBT2, anticorps PPND, anticorps TAU, anticorps tau, anticorps PHF-tau, anticorps microtubule associated protein tau, anticorps MAPT

Poids moléculaire: 80kDa

ID gène: 4137

UniProt: P10636