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COPS3 anticorps (AA 261-360) (Biotin)

COPS3 Reactivité: Humain ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN4908228
  • Antigène Voir toutes COPS3 Anticorps
    COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
    Épitope
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 261-360
    Reactivité
    • 48
    • 21
    • 21
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 5
    • 1
    Lapin
    Clonalité
    • 44
    • 4
    Polyclonal
    Conjugué
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COPS3 est conjugé à/à la Biotin
    Application
    • 27
    • 14
    • 13
    • 12
    • 12
    • 11
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human COPS3
    Isotype
    IgG
    Top Product
    Discover our top product COPS3 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
    Autre désignation
    COPS3 (COPS3 Produits)
    Synonymes
    anticorps CG18332, anticorps CH3, anticorps Csn3, anticorps DCH3, anticorps Dch3, anticorps Dmel\\CG18332, anticorps FBgn0027055, anticorps dCSN3, anticorps COPS3, anticorps CSN3, anticorps DKFZp468P1922, anticorps Sgn3, anticorps wu:fc32a02, anticorps wu:fk59f01, anticorps zgc:111903, anticorps zgc:55643, anticorps zgc:77615, anticorps CONSTITUTIVE PHOTOMORPHOGENIC 13, anticorps COP9 SIGNALOSOME SUBUNIT 3, anticorps F18O22.40, anticorps F18O22_40, anticorps FUS11, anticorps FUSCA 11, anticorps SGN3, anticorps csn3, anticorps COP9 signalosome subunit 3, anticorps Proteasome component (PCI) domain protein, anticorps COP9 signalosome subunit 3 L homeolog, anticorps COP9 signalosome complex subunit 3, anticorps CSN3, anticorps cops3, anticorps COPS3, anticorps Cops3, anticorps COP13, anticorps cops3.L, anticorps csn-3
    Sujet

    Synonyms: COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    ID gène
    8533
    Pathways
    Cycle Cellulaire
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