CR1L anticorps (AA 51-150) (Biotin)

N° du produit ABIN4908341

Détail du produit anti-CR1L anticorps (Biotin)

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Épitope: AA 51-150

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CR1L est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Crry

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CR1L

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Autre désignation: Crry (CR1L Produits)

Synonymes: anticorps CREG, anticorps Cr1, anticorps Crry, anticorps Mcp, anticorps mCRY, anticorps complement C3b/C4b receptor 1 like, anticorps complement component (3b/4b) receptor 1-like, anticorps CR1L, anticorps Cr1l

Sujet:

Synonyms: Mcp, Crry, mCRY, Complement component receptor 1-like protein, Complement regulatory protein Crry, Protein p65, Cr1l, Cry

Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.

ID gène: 12946

UniProt: Q64735

Pathways: Système du Complément