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- Antigène Voir toutes RNF20 Anticorps
- RNF20 (Ring Finger Protein 20 (RNF20))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp RNF20 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Purified by Protein G.
- Immunogène
- This RNF20 antibody is generated from a mouse immunized with a recombinant protein of human RNF20.
- Clone
- 4C6
- Isotype
- IgG1
- Top Product
- Discover our top product RNF20 Anticorps primaire
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anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibody
RNF20 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (Internal Region) antibodyRNF20 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibodyRNF20 Reactivité: Humain IP Hôte: Lapin Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1E4 unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-260) antibodyRNF20 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 576-625) antibodyRNF20 Reactivité: Humain, Souris, Chien, Boeuf (Vache), Cobaye, Porc, Hamster, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 108-157) antibodyRNF20 Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Cobaye, Hamster, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (N-Term) antibodyRNF20 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- RNF20 (Ring Finger Protein 20 (RNF20))
- Autre désignation
- RNF20 (RNF20 Produits)
- Synonymes
- anticorps 4833430L21Rik, anticorps AW540162, anticorps C79397, anticorps mKIAA4116, anticorps BRE1, anticorps BRE1A, anticorps hBRE1, anticorps ring finger protein 20, anticorps RNF20, anticorps Rnf20
- Sujet
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Synonyms: BRE1, BRE1A, hBRE1, E3 ubiquitin-protein ligase BRE1A, BRE1-A, RING finger protein 20, RNF20
Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.
- ID gène
- 56254
- UniProt
- Q5VTR2
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