Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

SNX6 anticorps

SNX6 Reactivité: Humain WB Hôte: Souris Monoclonal 5T6 unconjugated
N° du produit ABIN4914189
  • Antigène Voir toutes SNX6 Anticorps
    SNX6 (Sorting Nexin 6 (SNX6))
    Reactivité
    • 34
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 27
    • 8
    Souris
    Clonalité
    • 27
    • 8
    Monoclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SNX6 est non-conjugé
    Application
    • 23
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain
    Purification
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    Immunogène
    This SNX6 monoclonal antibody is generated from mouse immunized with SNX6 recombinant protein.
    Clone
    5T6
    Isotype
    IgG1
    Top Product
    Discover our top product SNX6 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    SNX6 (Sorting Nexin 6 (SNX6))
    Autre désignation
    SNX6 (SNX6 Produits)
    Synonymes
    anticorps MGC75952, anticorps MGC80251, anticorps im:7146294, anticorps wu:fa55b10, anticorps zgc:110798, anticorps MSTP010, anticorps TFAF2, anticorps 2010006G21Rik, anticorps 2610032J07Rik, anticorps 2810425K19Rik, anticorps AU018928, anticorps C85963, anticorps sorting nexin 6, anticorps sorting nexin 6 L homeolog, anticorps snx6, anticorps snx6.L, anticorps SNX6, anticorps Snx6
    Sujet

    Synonyms: TFAF2, MSTP010, Sorting nexin-6, TRAF4-associated factor 2, SNX6

    Background: Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate (Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:19935774). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Does not have in vitro vesicle-to-membrane remodeling activity (PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R (PubMed:17148574). May function as link between transport vesicles and dynactin (Probable). Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network (PubMed:20354142). Involved in E-cadherin sorting and degradation, inhibits PIP5K1C isoform 3-mediated E-cadherin degradation (PubMed:24610942). In association with GIT1 involved in EGFR degradation. Promotes lysosomal degradation of CDKN1B (By similarity). May contribute to transcription regulation (Probable).

    ID gène
    58533
    UniProt
    Q9UNH7
    Pathways
    EGFR Signaling Pathway
Vous êtes ici:
Support technique