TRAF3 anticorps (AA 101-200) (PE)

N° du produit ABIN4914800

Détail du produit anti-TRAF3 anticorps (PE)

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Épitope: AA 101-200

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3 est conjugé à/à la PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRAF3

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TRAF3

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Autre désignation: TRAF3 (TRAF3 Produits)

Synonymes: anticorps CAP-1, anticorps CAP1, anticorps CD40bp, anticorps CRAF1, anticorps IIAE5, anticorps LAP1, anticorps AI528849, anticorps T-BAM, anticorps amn, anticorps TNF receptor associated factor 3, anticorps TNF receptor-associated factor 3, anticorps Tnf receptor-associated factor 3, anticorps TRAF3, anticorps Traf3

Sujet:

Synonyms: CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp, TNF receptor-associated factor 3, CD40 receptor-associated factor 1, CD40-binding protein, LMP1-associated protein 1, TRAF3

Background: Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.

ID gène: 7187

UniProt: Q13114

Pathways: Signalisation NF-kappaB, Apoptose, Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades