LY96 anticorps (AA 2-160)

N° du produit ABIN492533

Détail du produit anti-LY96 anticorps

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Épitope: AA 2-160

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LY96 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Attributs du produit: Synonyms: Lymphocyte antigen 96, ESOP-1, LY96, ESOP1, MD2

Purification: Immunoaffinity Chromotography.

Immunogène: A recombinant protein corresponding to amino acids 2 to 160 of Human MD-2 (NP_056179).

Clone: 9F1B1

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: MD2 antibody can be used for detection of MD2 at 0.5-1 μg/mL. Immunohistochemistry: 2.5 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur LY96

Antigène: LY96 (Lymphocyte Antigen 96 (LY96))

Autre désignation: MD-2 (LY96 Produits)

Synonymes: anticorps MD2, anticorps ESOP-1, anticorps MD-2, anticorps ly-96, anticorps Ly-96, anticorps Md2, anticorps lymphocyte antigen 96, anticorps LY96, anticorps Ly96

Sujet: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2, e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.Synonyms: ESOP-1, ESOP1, LY96, Lymphocyte antigen 96, MD2

UniProt: Q9Y6Y9

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades