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CFTR / Cystic Fibrosis Transmembrane Regulator anticorps

Reactivité: Humain, Souris IHC (p), IF, WB Hôte: Souris Monoclonal SPM176 unconjugated
N° du produit ABIN4949559
  • Antigène
    CFTR / Cystic Fibrosis Transmembrane Regulator
    Reactivité
    Humain, Souris
    Hôte
    • 5
    • 4
    Souris
    Clonalité
    • 9
    Monoclonal
    Conjugué
    • 9
    Inconjugué
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Western Blotting (WB)
    Purification
    Protein G affinity chromatography
    Immunogène
    Human partial recombinant protein was used as the immunogen for this CFTR antibody.
    Clone
    SPM176
    Isotype
    IgG2a
  • Indications d'application
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. IF: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène
    CFTR / Cystic Fibrosis Transmembrane Regulator
    Sujet
    Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
    ID gène
    1080
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