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CFTR / Cystic Fibrosis Transmembrane Regulator anticorps

Reactivité: Humain IHC (p), IF, WB Hôte: Souris Monoclonal CFTR-1341 unconjugated
N° du produit ABIN4949561
  • Antigène
    CFTR / Cystic Fibrosis Transmembrane Regulator
    Reactivité
    • 9
    • 4
    Humain
    Hôte
    • 5
    • 4
    Souris
    Clonalité
    • 9
    Monoclonal
    Conjugué
    • 9
    Inconjugué
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Western Blotting (WB)
    Purification
    Protein G affinity chromatography
    Immunogène
    Human recombinant protein was used as the immunogen for this CFTR antibody.
    Clone
    CFTR-1341
    Isotype
    IgG1
  • Indications d'application
    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.\. Immunofluorescence: 1-2 μg/mL,Western blot: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène
    CFTR / Cystic Fibrosis Transmembrane Regulator
    Sujet
    Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
    ID gène
    1080
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