Thrombomodulin anticorps (AA 69-194)

N° du produit ABIN4949900

Détail du produit anti-Thrombomodulin anticorps

Antigène: Thrombomodulin (THBD)

Épitope: AA 69-194

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thrombomodulin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogène: Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.

Clone: THBD-1591

Isotype: IgG2b kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Thrombomodulin antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT,ELISA: 2-4 μg/mL, order the BSA-free formulation for coating,WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Thrombomodulin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Thrombomodulin

Antigène: Thrombomodulin (THBD)

Autre désignation: Thrombomodulin / CD141 (THBD Produits)

Synonymes: anticorps AHUS6, anticorps BDCA3, anticorps CD141, anticorps THPH12, anticorps THRM, anticorps TM, anticorps AI385582, anticorps THBD, anticorps HAST, anticorps HAST3, anticorps M-PST, anticorps ST1A3/ST1A4, anticorps ST1A5, anticorps STM, anticorps TL-PST, anticorps thrombomodulin, anticorps sulfotransferase family 1A member 3, anticorps THBD, anticorps Thbd, anticorps SULT1A3

Sujet: It recognizes a protein of 75  kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.