OPA1 anticorps
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- Antigène Voir toutes OPA1 Anticorps
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp OPA1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- Amino acids EDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEA of human OPA1 were used as the immunogen for the OPA1 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product OPA1 Anticorps primaire
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- Indications d'application
- Optimal dilution of the OPA1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the OPA1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))
- Autre désignation
- OPA1 (OPA1 Produits)
- Synonymes
- anticorps 1200011N24Rik, anticorps AI225888, anticorps AI847218, anticorps lilr3, anticorps mKIAA0567, anticorps MGM1, anticorps NPG, anticorps NTG, anticorps largeG, anticorps fk62d06, anticorps wu:fb77a10, anticorps wu:fk62d06, anticorps zgc:92092, anticorps OPA1, mitochondrial dynamin like GTPase, anticorps optic atrophy 1 (autosomal dominant), anticorps Opa1, anticorps OPA1, anticorps opa1
- Sujet
- Dynamin-like 120 kDa protein, mitochondrial is a protein that in humans is encoded by the OPA1 gene. It is mapped to 3q29. This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
- UniProt
- O60313
- Pathways
- Tube Formation
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