SIRT6 anticorps
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- Antigène Voir toutes SIRT6 Anticorps
- SIRT6 (Sirtuin 6 (SIRT6))
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Reactivité
- Humain, Souris, Rat, Primate
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SIRT6 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Purification
- Protein G affinity
- Immunogène
- A human recombinant protein was used as the immunogen for this SIRT6 antibody.
- Clone
- 6C9-D10-D3
- Isotype
- IgG1
- Top Product
- Discover our top product SIRT6 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable
- Restrictions
- For Research Use only
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- Buffer
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
- Stock
- -20 °C
- Stockage commentaire
- Store the SIRT6 antibody at -20°C.
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- Antigène
- SIRT6 (Sirtuin 6 (SIRT6))
- Autre désignation
- SIRT6 (SIRT6 Produits)
- Synonymes
- anticorps 2810449N18Rik, anticorps AI043036, anticorps Sir2l6, anticorps SIR2L6, anticorps zgc:86729, anticorps sirtuin 6, anticorps sirtuin 6 S homeolog, anticorps Sirt6, anticorps SIRT6, anticorps sirt6.S, anticorps sirt6
- Sujet
- NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]
- UniProt
- Q8N6T7
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