×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
ADAM17 anticorps (AA 794-823)
ADAM17
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN3029859
Détail du produit anti-ADAM17 anticorps
(cache)
Antigène
Voir toutes ADAM17 Anticorps
ADAM17
(ADAM Metallopeptidase Domain 17 (ADAM17))
Épitope
Tous les épitopes à travers ADAM17 Anticorps.
AA 794-823
Reactivité
Toutes les réactivités sur ADAM17 Anticorps
Humain
Hôte
Toutes les hôtes sur ADAM17 Anticorps
Lapin
Clonalité
Toutes les clonalités sur ADAM17 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers ADAM17 Anticorps
Cet anticorp ADAM17 est non-conjugé
Application
Tous les applications à travers ADAM17 Anticorps.
Western Blotting (WB), ELISA
Purification
Antigen affinity purified
Immunogène
A portion of amino acids 794-823 from the human protein was used as the immunogen for this ADAM17 antibody.
Isotype
Ig Fraction
Top Product
Discover our top product ADAM17 Anticorps primaire
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Titration of the ADAM17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the ADAM17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Détails sur ADAM17
(cache)
Antigène
ADAM17
(ADAM Metallopeptidase Domain 17 (ADAM17))
Autre désignation
ADAM17 (ADAM17 Produits )
Synonymes
anticorps ADAM18, anticorps CD156B, anticorps CSVP, anticorps NISBD, anticorps TACE, anticorps CD156b, anticorps Tace, anticorps adam17, anticorps si:dkey-81b15.2, anticorps adam18, anticorps cd156b, anticorps csvp, anticorps tace, anticorps fc20b01, anticorps wu:fc20b01, anticorps zgc:63886, anticorps ADAM metallopeptidase domain 17, anticorps a disintegrin and metallopeptidase domain 17, anticorps ADAM metallopeptidase domain 17b, anticorps ADAM metallopeptidase domain 17 L homeolog, anticorps ADAM metallopeptidase domain 17a, anticorps ADAM17, anticorps Adam17, anticorps adam17b, anticorps adam17.L, anticorps adam17a
Sujet
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2. [UniProt]
UniProt
P78536
Pathways
Signalisation Notch , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Response to Growth Hormone Stimulus
Vus récemment
(cache)